Plasma exchange complications in patients treated for thrombotic thrombocytopenia purpura-hemolytic uremic syndrome: 2011 to 2014.

contrast to previous publications, which identified arterial events with higher rates than venous events. This discrepancy may indicate that the high number of venous TEEs observed by Sridhar and colleagues may have been largely driven by cases of phlebitis or thrombophlebitis. Unfortunately, separate numbers for these types of events have not been provided by the authors. Pooling events such as myocardial infarction or deep vein thrombosis with events such as phlebitis and thrombophlebitis, which may be attributable to potentially different risk factors, does not allow for making a clear distinction between events associated with IGs themselves versus events that may be associated with the devices used for administering IGs. Estimates for peripheral venous catheter– associated thrombophlebitis rates range from 2% to 80%, and the risk of these events is correlated with the site and size of the catheter.